Formulation and Optimization of Zidovudine Niosomes
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Niosomes
Span 20-based niosome was prepared by lipid film hydration technique and loaded with Newcastle disease vaccine. Three batches with Span 20, cholesterol and dicetyl phosphate in micro molar ratios of 10:10:1; 15:15:1 and 20:20:1 were prepared and evaluated for encapsulation efficiency using haemagglutination test. The morphology of the vesicles was studied by means of transmission electron micro...
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To prepare niosomes containing rifampicin were prepared using various nonionic surfactants of sorbitan ester class and cholesterol in 50:60 (1:1.2) percent mol fraction ratios for sustain release. To improve the dissolution rate of noisome are prepare handshaking method using Surfactants and cholesterol (150 μmol) in 50:60 (1:1.2) percent mol fraction ratio. The percent of drug estimated to be ...
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The goal of the present study was to investigate the feasibility of using non-ionic surfactant vesicles as carriers for the sustained delivery of water soluble anti-cancer drug Capecitabine, used in the treatment of colorectal cancer. The niosomal formulations were prepared using various non-ionic surfactants (span 40, span 60, tween 40 and tween 60) in the presence of cholesterol, by thin film...
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Zidovudine is an antiretroviral drug commonly used in the treatment HIV infection. But it is very bitter in taste and sparingly soluble in water. Thus the purpose of this investigation was to formulate and evaluate taste masked dispersible tablets of zidovudine. Dispersible tablets of zidovudine were prepared using crosscarmellose sodium (Ac-di-sol) as disintegrant. Surelease clear (E-7-19010) ...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2010
ISSN: 1530-9932
DOI: 10.1208/s12249-010-9480-2